Can Ozempic Decrease Violent Behavior?

The Journal of Criminology published a study suggesting GLP-1 drugs might potentially curb people’s violent tendencies.

Scientists at Rutgers University examined nationally representative survey data that compared former and current GLP-1 users. In people currently taking GLP-1s, they found, the link between being impulsive and being more prone to violence was noticeably weaker. These potential benefits in reducing addiction likely stem from how the drugs can affect people’s sense of impulse control and reward processing.

GLP-1 DRUGS AND BEHAVIOR

GLP-1s, by virtue of treating weight loss, can treat or reduce the risk of many health conditions closely tied to obesity, such as heart disease or knee pain. Some research, however, has also indicated these drugs have behavioral effects that go beyond simply reducing a person’s appetite. Numerous studies have found evidence that GLP-1s can decrease people’s harmful cravings for alcohol or other recreational drugs, for instance.

“As criminologists and violence researchers, that caught our attention because impulsivity and alcohol use are among the most established behavioral risk factors for violence. “We wanted to explore whether GLP-1 use might be associated with changes in the relationship between those risk factors and violent behavior. To our knowledge, no previous study had examined that question directly.” ~Daniel Semenza, Director of Research at the New Jersey Gun Violence Research Center at the Rutgers School of Public Health.

THE STUDY’S METHODOLOGY

The study reviewed data collected from a nationally representative survey of 7,521 U.S. adults. They specifically looked at 821 people who reported ever having taken a GLP-1, including 597 people currently on one. People were asked questions about their alcohol use and level of impulsivity, such as whether they would enjoy being in a high-speed chase or a fistfight. They were also asked (with a guarantee of confidentiality) if they had taken part in various violent crimes sometime in the past year.

Sure enough, the researchers noticed a sizeable difference between people taking a GLP-1 and people who used GLP-1s in the past but are no longer taking them.

“Among former users, people with higher levels of impulsivity and alcohol use reported much higher levels of violent behavior, which is consistent with decades of prior research. Among current users, those relationships were much less pronounced.” ~ Daniel Semenza

Overall, the link between impulsivity and violence was about 62% weaker in current GLP-1 users, while the link between alcohol use and violence was 52% weaker. That said, after conducting further analysis, there was less clear evidence of GLP-1s specifically affecting the relationship between alcohol use and violent behavior.

My opinion? Despite the findings, scientists still have a lot to learn about how these increasingly popular drugs could affect behavior in general. We’re only beginning to understand the broader behavioral effects of these medications. Much more research is needed before drawing firm conclusions.

Please contact my office if you, a friend or family member are charged with Assault or any other violent crime. Hiring an effective and competent defense attorney is the first and best step toward justice.

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Alexander Ransom